![]() ![]() These are available only by prescription. Nasal spray antihistamines are also somewhat less likely to make you sleepy, since they target nasal passages directly rather than sending medicine throughout your body in the bloodstream. An added benefit is that second-generation antihistamines last longer than Benadryl. Newer, second-generation antihistamines such as cetirizine (Zyrtec®), fexofenadine (Allegra®) and loratadine (Claritin®) – marketed as “nonsedating” – usually cause less drowsiness. ![]() Currently, there is no non-drowsy Benadryl® on the market. On the other hand, if one doesn’t work for you, try another type.ĭoes diphenhydramine (Benadryl®) make you sleepy? First-generation antihistamines such as diphenhydramine (Benadryl®) usually cause drowsiness because they are less likely to affect the histamine produced in the brain or have other unwanted effects in the brain. When you find one that works for you, stick with it – check chemical ingredients and dosages before changing brands or generics. What relieves your symptoms without making you sleepy may be different from what works for someone else. Reactions vary considerably from one person to another. Some antihistamines are less likely to cause drowsiness than others. What can you do about drowsiness from allergy medicines? Antihistamines used to treat respiratory symptoms can get into the brain and interrupt this work, making you feel drowsy. Unrelated to the immune system, histamine is also produced in the brain, where it plays an important part in feeling awake. Antihistamine medications relieve these symptoms by blocking the unwanted effects of histamine. In its search-and-destroy process, it can cause allergy or cold symptoms such as runny nose, coughing, sneezing and itch eyes. When there is a threat of allergies or infection (such as the common cold), histamine is even more active. ![]() How does this happen? Histamine is a chemical produced by the immune system to fight off allergens and germs. In treating allergies or a cold with antihistamines, you may experience drowsiness, a common side effect of the medication. 4 Be smart, be aware of allergy medication side effects Tips for Staying Alert ![]()
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